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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNE1
All Species:
7.27
Human Site:
S109
Identified Species:
12.31
UniProt:
P24864
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24864
NP_001229.1
410
47077
S109
G
S
P
L
P
V
L
S
W
A
N
R
E
E
V
Chimpanzee
Pan troglodytes
XP_512559
393
44800
L103
E
E
V
W
K
I
M
L
N
K
E
K
T
Y
L
Rhesus Macaque
Macaca mulatta
XP_001084995
410
47103
S109
G
S
P
L
P
V
L
S
W
A
N
R
E
E
V
Dog
Lupus familis
XP_541724
456
51105
N155
A
S
P
L
P
L
L
N
W
A
N
R
D
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61457
408
46968
L106
R
A
S
P
L
P
V
L
N
W
G
N
R
E
E
Rat
Rattus norvegicus
P39949
411
47463
L109
R
A
S
P
L
P
V
L
N
W
A
N
R
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507249
405
46635
S107
P
S
P
L
P
D
L
S
W
G
C
S
N
D
V
Chicken
Gallus gallus
P49707
407
46720
G106
S
S
P
L
P
I
L
G
W
A
N
R
D
D
V
Frog
Xenopus laevis
Q91780
408
47153
G108
V
S
P
L
P
R
L
G
W
A
N
Q
D
D
V
Zebra Danio
Brachydanio rerio
P47794
410
46612
C111
S
T
P
L
P
A
L
C
W
A
S
K
D
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54733
709
77202
A324
Q
C
P
L
P
A
L
A
W
A
N
A
A
D
V
Honey Bee
Apis mellifera
XP_394802
457
51232
L111
T
S
N
R
P
S
P
L
P
S
F
P
W
A
D
Nematode Worm
Caenorhab. elegans
O01501
524
60567
G199
D
Y
P
V
Q
N
E
G
F
A
V
T
K
R
L
Sea Urchin
Strong. purpuratus
XP_785047
424
48468
H120
A
S
P
V
P
L
L
H
W
D
D
L
P
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
98.2
73.9
N.A.
78.7
79.5
N.A.
49
71.9
60.2
58.2
N.A.
28.2
38.2
24.2
44.5
Protein Similarity:
100
95.3
98.5
81.1
N.A.
88.7
90
N.A.
66.5
85.1
76.8
73.9
N.A.
39.6
55.1
41.4
60.8
P-Site Identity:
100
0
100
73.3
N.A.
6.6
6.6
N.A.
53.3
66.6
60
53.3
N.A.
53.3
13.3
13.3
46.6
P-Site Similarity:
100
26.6
100
93.3
N.A.
20
20
N.A.
60
86.6
80
80
N.A.
66.6
20
40
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
0
0
0
15
0
8
0
58
8
8
8
8
0
% A
% Cys:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
0
0
8
8
0
29
29
8
% D
% Glu:
8
8
0
0
0
0
8
0
0
0
8
0
15
50
15
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% F
% Gly:
15
0
0
0
0
0
0
22
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
8
0
15
8
0
0
% K
% Leu:
0
0
0
58
15
15
65
29
0
0
0
8
0
0
15
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
8
22
0
43
15
8
0
0
% N
% Pro:
8
0
72
15
72
15
8
0
8
0
0
8
8
0
0
% P
% Gln:
8
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
15
0
0
8
0
8
0
0
0
0
0
29
15
8
0
% R
% Ser:
15
58
15
0
0
8
0
22
0
8
8
8
0
0
0
% S
% Thr:
8
8
0
0
0
0
0
0
0
0
0
8
8
0
0
% T
% Val:
8
0
8
15
0
15
15
0
0
0
8
0
0
0
65
% V
% Trp:
0
0
0
8
0
0
0
0
65
15
0
0
8
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _